About Core Shell Particles
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Core-shell particles consist of a nonporous core inside a porous shell. By using these core-shell particles, one can achieve sharper peaks compared to fully porous silica gel particles of the same diameter. |
• COSMOCORE Method Development Kit
Uniform Particle Size Distribution Compared to 1.7 µm Particles
Compared to fully porous particles, core-shell particles have a more uniform particle diameter therefore, core-shell particles can be packed in the column more uniformly to minimize sample diffusion.
COSMOCORE 2.6C18 (200x) Fully porous 1.7 µm particles (200x)
Mass Transfer Equivalent to Fully Porous sub-2 µm Particles
Mass transfer refers to the time it takes for a sample molecule to enter and leave a particle. In general, lower mass transfer time corresponds to less diffusion and sharper peaks. Even though COSMOCORE 2.6C18 has a larger particle diameter than fully porous sub-2 µm particles, the mass transfer characteristics are similar.
COSMOCORE 2.6C18 Fully porous sub-2 µm particle
COSMOCORE UHPLC Columns (Specifications)
| Column | COSMOCORE 2.6C18 | COSMOCORE 2.6Cholester | COSMOCORE 2.6PBr |
|---|---|---|---|
| USP Code | L 1 | L 101 | |
| Silica gel | Core-Shell type silica | ||
| Particle size | 2.6 µm | ||
| Core average diameter | 1.6 µm | ||
| Average pore size | approx. 90Å | ||
| Specific surface area | approx. 300 m²/g | ||
| Stationary phase |
Octadecyl Group |
Cholesteryl Group |
Pentabromobenzyl group |
| Main Interaction | Hydrophobic interaction |
Hydrophobic interaction
Molecular shape selectivity
|
Hydrophobic interaction Dispersion force |
| Endcapping treatment | Near-Perfect Treatment | ||
| Carbon content | approx. 7% | - | - |
| pH range | 1.5 - 10.0 | 2 - 7.5 | 2 - 7.5 |
| Max. Pressure | 60 MPa | ||
• COSMOCORE Method Development Kit
COSMOSIL Application Search
COSMOSIL Application, which includes more than 7,700 applications using COSMOSIL/COSMOCORE columns, is now usable by clicking the link below which is in Nacalai Tesque, Inc. The application is searchable by sample category, sample name, CAS No., column name and particle size
