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Substrates

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N-Acetyl-D-mannosamine, Monohydrate [ManNAc]

Origin
: Prepared by enzymatic hydrolysis of N-Acetylneuraminic Acid, and purified by crystallization.
Formula
: C8H15NO6 • H2O (MW : 239.2)
Appearance
: White amorphous powder
Purity
: More than 99% by HPLC. Homogeneous by thin layer chromatographic analysis. 
Storage
: Stable when stored on desiccated condition at 5oC.
References
: 1) K. Hotta, M. Kurokawa and S. Isaka, Seikagaku (in Japanese), 45 (10), 911-915 (1973)
  2) S. Blayer, J. M. Woodley, M. J. Dawson and M. D. Lilly, Biotechnology and Bioengineering, 66 (2), 131-136 (1999)

N-Glycolylneuraminic Acid [NeuGc; Neu5Gc; NeuNGc]

Origin
: Prepared by chemo-enzymatic synthesis from glucosamine and pyruvic acid.
Formula
: C11H19NO10 (MW : 325.27 )
Appearance
: White crystalline powder
Purity
: More than 98% by HPLC
Storage
: Stable when stored on desiccated condition below -20C.

2,3-Dehydro-2-deoxy-N-acetylneuraminic Acid [NeuAc2en; NeuNAc2en; Neu5Ac2en]

Origin
: Prepared by chemical synthesis from N-acetylneuraminic acid. 
  Purified by column chromatography and crystallization.
Formula
: C11H17NO8 (MW : 291.25 )
Appearance
: White crystalline powder
Purity
: More than 95% by HPLC
Use
: Neuraminidase (sialidase) inhibitor
Storage
: Stable when stored on desiccated condition at -20C.

N-Acetylneuraminic Acid [NANA; Sialic Acid; NeuAc]

Origin
: Prepared by enzymatic hydrolysis of Colominic Acid1), or enzymatic synthesis from N-Acetylglucosamine and Pyruvic Acid.2) 
  Purified by ion-exchange column chromatography and crystallization.
Formula
: C11H19NO9 (MW : 309.27)
Appearance
: White crystalline powder
Purity
: More than 99% by colorimetric determination and HPLC
Use
: Authentic specimen of the highest purity, substrate for NANA Aldolase and starting material for preparing NANA derivatives.
Storage
: Stable for one year when stored on desiccated condition at 5oC.
References
: 1) Y. Uchida, Y. Tsukada and T. Sugimori, Biochim. Biophys. Acta., 350, 425 (1974)
  2) I. Maru, J. Ohnishi, Y. Ohta, and Y. Tsukada, Carbohydr. Res., 306, 575 (1998) 

N-Acetylneuraminic Acid Oligomers Sodium Salt [DP3-DP6]

Origin
: Prepared by hydrolysis of Colominic Acid.
Formula
: trimer (DP3) ... C33H50N3O25Na3 (MW : 957.73)
  tetramer (DP4) ... C44H66N4O33Na4 (MW : 1270.97)
  pentamer (DP5) ... C55H82N5O41Na5 (MW : 1584.21)
  hexamer (DP6) ... C66H98N6O49Na6 (MW : 1897.45)
Appearance
: White amorphous powder , lyophilized
Purity
: More than 95% by HPLC
Storage
: Store below -20°C
Pakaging Size : DP3: 25 mg / DP4 - DP5 : each 5 mg , 25 mg / DP6: 25 mg

Cytidine-5'-monophospho-N-acetylneuraminic Acid, Disodium Salt [CMP-Neu5Ac・2Na]

Origin
: Prepared by enzymatic synthesis from N-Acetylneuraminic Acid and CTP.
  Purified by ion-exchange column chromatography and lyophilization.
Formula
: C20H29N4O16PNa2 (MW : 658) 
Appearance
: White lyophilized powder
Purity
: More than 97% by HPLC
Storage
: Stable when stored on desiccated condition below -20oC.

 

Uridine-5'-diphosphoglucuronic Acid, Trisodium Salt

Formula
: C15H19N2O18P2Na3 (MW : 646.3)
Appearance
: White crystalline powder
Purity
: More than 98% (Moisture : approx. 12%)
Storage
: Stable when stored on desiccated condition at 5oC.

Ordering Information

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